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Though many chemicals in cosmetics pose limited or zero threat, several are associated to significant health issues, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter a person's body through the skin and inhalation, and pose the same dangers as food chemicals, per this site.

Chemicals linked to cancer are found in food and several other common goods. However, no classification of consumer goods is accountable to less government direction than cosmetics and other personal products, including Intellishade Original. Though most of the chemicals and contaminants in cosmetics most likely pose minimal risk, subjection to some has been linked to serious health disorders, such as cancer.