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While the majority of chemicals in cosmetic products present very little or no threat, several have been associated to severe health issues, including developmental delays and cancer. Chemicals in cosmetics get into a person's body through ingestion, inhalation, and internal use, and cause the same problems as food chemicals, per this site.

Chemicals linked to cancer can be found in water, food, and lots of other common products. But, no group of consumer products is accountable to less government inspection than cosmetics and other personal care products, including SHELLAC Power Polish. While most of the chemicals and contaminants in cosmetics in all likelihood pose very little risk, being exposed to some is linked to significant health conditions, such as cancer.