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Though most chemicals in cosmetic products pose very little or zero threat, dozens have been associated to significant health conditions, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter a person's body through the skin and inhalation, and cause similar problems as food chemicals, per this site.

Chemicals associated with cancer are found in food and many other everyday goods. But, no sector of consumer goods is susceptible to less government management than cosmetics, including Santa Bomb Bombs. While most of the chemicals in cosmetics likely present minimal risk, being exposed to a few has been associated with critical health conditions, including cancer.