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Though most chemicals in cosmetics pose little or absolutely no threat, some have been associated to substantial health issues, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to a person's body through internal use, the skin, and inhalation, and lead to similar risks as food chemicals, per this site.

Chemicals linked to cancer are found in food, water, and lots of other commonly used items. However, no type of consumer items is subject to less government direction than cosmetics, including Seven Deadly Spins. While most of the chemicals and contaminants in cosmetics and personal care products most likely present minimal risk, being exposed to some has been linked to serious health disorders, including cancer.