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Although many chemicals in cosmetic products pose minimal or no danger, dozens have been linked with significant health conditions, such as developmental delays and cancer. Chemicals in cosmetics can enter the body through inhalation, ingestion, and the skin, and lead to similar problems as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in food and various other common products. However, no type of consumer products is susceptible to less government management than cosmetics, including Girls' Night Out. While most of the chemicals in cosmetics likely pose very little risk, exposure to a few is linked to major health concerns, including cancer.