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Although the majority of chemicals in beauty products and cosmetics present very little or zero risk, several are associated to significant health conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to a person's body through inhalation, ingestion, and the skin, and cause the same problems as food chemicals, per this site.

Chemicals linked to cancer are found in water, food, and many other commonly used goods. Still, no category of consumer goods is susceptible to less government inspection than cosmetics and other personal products, including Girls' Night Out. While most of the contaminants and chemicals in cosmetics very likely present very little risk, being exposed to some has been linked to serious health conditions, such as cancer.