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Although the majority of chemicals in cosmetic products present limited or zero danger, several have been associated to considerable health problems, such as neurological harm and cancer. Chemicals in cosmetics can enter the body through inhalation, the skin, and ingestion, and pose similar problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in food and many other common items. However, no area of consumer items is accountable to less government direction than cosmetics and other personal products, including Sugar N' Spice & Everything Nice. While many of the chemicals in cosmetics and personal care products probably pose minimal risk, being exposed to some has been associated with major health conditions, such as cancer.