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Though most chemicals in cosmetics pose limited or zero threat, some have been associated to serious health issues, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals enter a person's body through inhalation, ingestion, and the skin, and pose the same problems as food chemicals, per this site.

Chemicals linked to cancer can be found in food and many other commonly used products. Still, no area of consumer products is accountable to less government management than cosmetics and other personal care products, including Heart Of Chrome. While most of the chemicals in cosmetics in all likelihood present very little risk, exposure to a few has been linked to worrying health concerns, such as cancer.