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Although most chemicals in beauty products and cosmetics pose hardly any or zero risk, several dozen have been associated with serious medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals gain entry to a person's body through inhalation, ingestion, and the skin, and cause the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food, water, and several other common items. Still, no sector of consumer items is accountable to less government direction than cosmetics, including Petal to the Metal. While most of the chemicals in cosmetics almost certainly present minimal risk, exposure to some is associated with significant health disorders, such as cancer.