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Although many chemicals in cosmetics pose very little or no risk, several have been associated to serious medical conditions, including cancer, and neurological harm. Chemicals in cosmetics invade a person's body through the skin and inhalation, and cause the same problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in water, food, and various other everyday items. However, no type of consumer items is subject to less government oversight than cosmetics and other personal products, including Sally Hansen Quick Care Seal & Shine Topcoat. While most of the chemicals in cosmetics and personal care products in all likelihood present little risk, subjection to a few is associated with substantial health concerns, including cancer.