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Though the majority of chemicals in beauty products and cosmetics present minimal or no danger, some have been associated with severe medical issues, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals enter a person's body through the skin, inhalation, ingestion and internal use, and lead to similar risks as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in food, water, and many other everyday goods. However, no group of consumer goods is accountable to less government management than cosmetics and other personal care products, including Uptown. While most of the chemicals in cosmetics almost certainly pose little risk, subjection to some has been associated with critical health conditions, including cancer.