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While the majority of chemicals in cosmetics pose very little or no threat, several dozen are associated to considerable medical problems, including developmental delays and cancer. Cosmetic chemicals gain entry to the body through the skin and inhalation, and pose the same dangers as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food, water, and lots of other commonly used items. Still, no category of consumer items is accountable to less government inspection than cosmetics, including I Wear The Pants. While most of the chemicals and contaminants in cosmetics probably pose minimal risk, exposure to a few is associated with serious health conditions, such as cancer.