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While most chemicals in beauty products present very little or no risk, dozens have been associated with severe health issues, including neurological harm and cancer. Cosmetic chemicals enter the body through inhalation, ingestion, and the skin, and lead to the same risks as food chemicals, per this site.

Chemicals associated with cancer can be found in food and many other commonly used goods. Yet, no group of consumer goods is susceptible to less government inspection than cosmetics, including Polka Dottie Hottie. While most of the chemicals in cosmetics probably present little risk, being exposed to some has been associated with worrying health disorders, including cancer.