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Although most chemicals in cosmetics present minimal or absolutely no risk, several dozen have been associated to serious health problems, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals get into a person's body through inhalation, ingestion, and the skin, and lead to the same risks as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and several other everyday products. Yet, no area of consumer products is subject to less government direction than cosmetics, including My Main Freeze. While most of the chemicals in cosmetics probably present very little risk, being exposed to some is associated with worrying health concerns, such as cancer.