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While most chemicals in cosmetics pose limited or zero threat, some are linked to substantial health problems, including neurological harm and cancer. Cosmetic chemicals gain entry to the body through the skin and inhalation, and pose the same risks as food chemicals, per this site.

Chemicals associated with cancer can be found in water, food, and many other commonly used goods. But, no category of consumer goods is subject to less government management than cosmetics and other personal care products, including Simply Irresistible. Although many of the chemicals and contaminants in cosmetics likely pose little risk, subjection to a few has been associated with serious health concerns, such as cancer.