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While most chemicals in cosmetic products present minimal or absolutely no threat, dozens have been associated with significant health issues, including developmental delays and cancer. Cosmetic chemicals enter a person's body through ingestion, inhalation, and internal use, and lead to the same dangers as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in water, food, and various other common goods. Still, no area of consumer goods is accountable to less government oversight than cosmetics, including Gossip Girl. While many of the contaminants and chemicals in cosmetics and personal care products most likely pose little risk, being exposed to a few is linked to worrying health problems, such as cancer.