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While many chemicals in cosmetics present slight or no risk, several dozen have been associated to substantial medical conditions, including neurological harm and cancer. Chemicals in cosmetics can enter a person's body through internal use, the skin, and inhalation, and cause the same dangers as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in water, food, and many other ordinary products. Yet, no classification of consumer products is subject to less government oversight than cosmetics and other personal care products, including Gossip Girl. Though many of the chemicals and contaminants in cosmetics and personal care products likely present very little risk, exposure to some has been linked to serious health issues, such as cancer.