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Although many chemicals in cosmetics pose limited or zero threat, several dozen have been linked to considerable medical conditions, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals can enter a person's body through ingestion, inhalation, and internal use, and cause similar problems as food chemicals, per this site.

Chemicals associated with cancer can be found in food and lots of other everyday items. However, no group of consumer items is accountable to less government oversight than cosmetics and other personal products, including Cheer Up Buttercup. While most of the chemicals in cosmetics in all likelihood pose minimal risk, being exposed to some is associated with critical health issues, such as cancer.