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Although the majority of chemicals in beauty products present hardly any or no danger, some are associated with considerable health problems, such as cancer, and neurological harm. Chemicals in cosmetics get into a person's body through ingestion, inhalation, and internal use, and pose similar dangers as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in water, food, and several other common goods. Yet, no kind of consumer goods is accountable to less government direction than cosmetics, including Rule the Runway. Although most of the chemicals and contaminants in cosmetics and personal care products probably pose little risk, subjection to some is associated with significant health problems, such as cancer.