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While many chemicals in cosmetics present very little or absolutely no risk, several have been linked with substantial health conditions, including neurological harm and cancer. Chemicals in cosmetics get into a person's body through ingestion, inhalation, and internal use, and lead to similar dangers as food chemicals, per this site.

Chemicals associated with cancer can be found in water, food, and many other everyday products. However, no classification of consumer products is susceptible to less government oversight than cosmetics, including Up In The Air-Heart. While most of the chemicals and contaminants in cosmetics and personal care products very likely present little risk, exposure to some has been associated with substantial health issues, including cancer.