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Though most chemicals in cosmetics present very little or no threat, some have been linked with substantial medical conditions, including neurological harm and cancer. Chemicals in cosmetics enter a person's body through internal use, the skin, and inhalation, and pose similar risks as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in food, water, and various other commonly used products. Yet, no kind of consumer products is accountable to less government direction than cosmetics, including Air Cushion Matte LongWear. Although most of the contaminants and chemicals in cosmetics and personal care products likely pose very little risk, subjection to some has been associated with worrying health problems, including cancer.