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Although most chemicals in cosmetic products pose minimal or zero risk, dozens have been associated with severe medical conditions, including cancer, and neurological harm. Chemicals in cosmetics get into a person's body through inhalation, the skin, and ingestion, and lead to the same problems as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in water, food, and lots of other everyday items. Yet, no sector of consumer items is susceptible to less government oversight than cosmetics, including Creative Play Base Coat. Although most of the chemicals in cosmetics and personal care products in all likelihood pose little risk, exposure to some is linked to major health problems, such as cancer.