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Though most chemicals in cosmetics pose slight or absolutely no risk, several have been associated to severe medical problems, including cancer, and neurological harm. Chemicals in cosmetics can enter the body through the skin, inhalation, ingestion and internal use, and lead to similar risks as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in water, food, and various other commonly used products. But, no classification of consumer products is susceptible to less government oversight than cosmetics and other personal products, including Creative Play Base Coat. Although most of the chemicals and contaminants in cosmetics probably pose little risk, subjection to some has been associated with serious health concerns, such as cancer.