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While the majority of chemicals in cosmetics present slight or no threat, several have been associated to severe health conditions, such as neurological harm and cancer. Chemicals in cosmetics gain entry to a person's body through the skin and inhalation, and cause similar problems as food chemicals, per this site.

Chemicals and contaminants linked to cancer can be found in food, water, and various other everyday goods. Yet, no classification of consumer goods is subject to less government direction than cosmetics and other personal care products, including Sparkly Pumpkin. Though many of the chemicals and contaminants in cosmetics and personal care products most likely pose very little risk, subjection to a few is linked to significant health issues, including cancer.