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Though most chemicals in cosmetic products pose little or absolutely no danger, dozens have been associated to substantial health conditions, including developmental delays and cancer. Chemicals in cosmetics can enter the body through inhalation, ingestion, and the skin, and cause the same risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in food and several other ordinary products. However, no area of consumer products is subject to less government oversight than cosmetics, including Smackers Nail Polish. Although most of the chemicals in cosmetics and personal care products in all likelihood pose very little risk, being exposed to some has been linked to critical health concerns, such as cancer.