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Though many chemicals in beauty products and cosmetics present minimal or zero threat, dozens are associated to serious medical issues, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter a person's body through ingestion, inhalation, and internal use, and lead to similar risks as food chemicals, per this site.

Chemicals linked to cancer are found in food, water, and a lot of other everyday goods. However, no kind of consumer goods is subject to less government management than cosmetics, including The Rough With The Smooth. While many of the chemicals and contaminants in cosmetics and personal care products most likely present very little risk, exposure to some is linked to critical health concerns, such as cancer.