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While most chemicals in cosmetics present slight or zero risk, several dozen have been associated to severe medical conditions, such as neurological harm and cancer. Cosmetic chemicals invade the body through internal use, the skin, and inhalation, and cause similar risks as food chemicals, per this site.

Chemicals associated with cancer are found in food and several other common items. However, no category of consumer items is subject to less government inspection than cosmetics, including Vichy LiftActiv Supreme. While most of the chemicals in cosmetics likely pose very little risk, being exposed to some is associated with worrying health conditions, such as cancer.