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While most chemicals in cosmetics pose very little or no risk, some are associated with considerable health issues, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals get into a person's body through inhalation, ingestion, and the skin, and cause the same risks as food chemicals, per this site.

Chemicals linked to cancer are found in water, food, and several other common items. Yet, no type of consumer items is accountable to less government inspection than cosmetics, including Pun Up Girl. While most of the chemicals in cosmetics most likely present very little risk, being exposed to some is linked to major health problems, such as cancer.