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Although the majority of chemicals in cosmetics present very little or zero risk, several dozen have been associated to significant health problems, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter the body through inhalation, the skin, and ingestion, and cause the same risks as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in water, food, and several other common goods. Still, no sector of consumer goods is subject to less government inspection than cosmetics and other personal care products, including Off The Cuff. Although most of the chemicals and contaminants in cosmetics likely present little risk, being exposed to some is linked to significant health problems, including cancer.