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Although many chemicals in cosmetic products present minimal or no danger, dozens have been associated with serious medical conditions, such as cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals invade a person's body through the skin and inhalation, and lead to similar problems as food chemicals, per this site.

Chemicals linked to cancer are found in water, food, and many other ordinary goods. But, no area of consumer goods is accountable to less government management than cosmetics, including Metallix Gleam. While many of the chemicals and contaminants in cosmetics and personal care products almost certainly pose very little risk, being exposed to a few is linked to critical health concerns, including cancer.