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While many chemicals in beauty products present very little or no threat, several have been linked with substantial health issues, including developmental delays and cancer. Chemicals in cosmetics enter a person's body through inhalation, the skin, and ingestion, and lead to similar dangers as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in water, food, and many other commonly used products. Still, no classification of consumer products is accountable to less government direction than cosmetics, including Five Inch Heels. While most of the chemicals and contaminants in cosmetics probably present minimal risk, being exposed to a few has been associated with substantial health concerns, such as cancer.