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Though the majority of chemicals in beauty products present little or zero threat, dozens have been linked with significant health issues, such as cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through the skin and inhalation, and cause similar dangers as food chemicals, per this site.

Chemicals linked to cancer are found in food, water, and many other everyday items. However, no kind of consumer items is subject to less government oversight than cosmetics, including SHISEIDO REFINING MAKEUP PRIMER. Although most of the chemicals and contaminants in cosmetics and personal care products in all likelihood pose minimal risk, your exposure to a few has been linked to major health concerns, including cancer.