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While most chemicals in cosmetics pose hardly any or no danger, several dozen are linked with significant health problems, including cancer, reproductive and neurological harm, and developmental delays. Cosmetic chemicals enter the body through the skin, inhalation, ingestion and internal use, and pose the same problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in water, food, and many other everyday goods. Yet, no group of consumer goods is subject to less government oversight than cosmetics and other personal products, including SHISEIDO REFINING MAKEUP PRIMER. Though most of the contaminants and chemicals in cosmetics and personal care products almost certainly pose minimal risk, subjection to a few has been associated with worrying health disorders, including cancer.