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While most chemicals in cosmetics present little or zero threat, some have been linked with substantial medical issues, including developmental delays and cancer. Cosmetic chemicals invade the body through the skin, inhalation, ingestion and internal use, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in food, water, and many other commonly used goods. Still, no kind of consumer goods is subject to less government direction than cosmetics and other personal care products, including SHISEIDO PERFECT REFINING FOUNDATION. While most of the contaminants and chemicals in cosmetics and personal care products most likely pose very little risk, your exposure to a few is linked to substantial health disorders, including cancer.