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While most chemicals in cosmetics pose very little or no threat, dozens are linked with considerable health problems, such as cancer, and neurological harm. Cosmetic chemicals can enter the body through inhalation, the skin, and ingestion, and lead to similar risks as food chemicals, per this site.

Contaminants and chemicals linked to cancer are found in water, food, and many other ordinary items. Yet, no type of consumer items is subject to less government management than cosmetics and other personal products, including Roxie's Hart. While many of the chemicals in cosmetics and personal care products in all likelihood present minimal risk, subjection to a few has been linked to substantial health conditions, including cancer.