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While most chemicals in cosmetics pose limited or no risk, several are associated to serious medical problems, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics get into a person's body through the skin, inhalation, ingestion and internal use, and pose the same dangers as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in water, food, and various other commonly used items. Still, no type of consumer items is accountable to less government management than cosmetics, including Chain Reaction. Although most of the contaminants and chemicals in cosmetics almost certainly pose very little risk, subjection to a few is associated with critical health conditions, such as cancer.