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Although many chemicals in cosmetic products present slight or no threat, some have been linked to considerable health problems, such as neurological harm and cancer. Chemicals in cosmetics enter the body through the skin and inhalation, and pose similar problems as food chemicals, per this site.

Chemicals linked to cancer can be found in food, water, and many other commonly used products. Yet, no sector of consumer products is susceptible to less government direction than cosmetics and other personal products, including Chain Reaction. While many of the chemicals in cosmetics most likely pose little risk, exposure to some is linked to major health conditions, such as cancer.