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Though the majority of chemicals in cosmetics pose little or no threat, several are associated with substantial medical conditions, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics enter a person's body through the skin and inhalation, and cause similar problems as food chemicals, per this site.

Chemicals linked to cancer are found in food, water, and several other ordinary products. However, no classification of consumer products is accountable to less government inspection than cosmetics, including Orange You Glad. While many of the chemicals in cosmetics in all likelihood present very little risk, subjection to a few has been linked to critical health conditions, such as cancer.