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Though many chemicals in cosmetic products present slight or zero threat, several have been linked with significant health issues, such as cancer, and neurological harm. Cosmetic chemicals enter the body through internal use, the skin, and inhalation, and lead to similar problems as food chemicals, per this site.

Contaminants and chemicals associated with cancer are found in food, water, and various other common goods. However, no category of consumer goods is accountable to less government direction than cosmetics, including Color Me Bold. Although most of the contaminants and chemicals in cosmetics almost certainly pose little risk, subjection to some has been associated with major health problems, such as cancer.