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Although most chemicals in cosmetics present minimal or no threat, some are associated to severe health problems, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter the body through the skin, inhalation, ingestion and internal use, and pose the same problems as food chemicals, per this site.

Chemicals and contaminants linked to cancer are found in food, water, and several other ordinary products. But, no area of consumer products is accountable to less government oversight than cosmetics, including I'm Charmed. While most of the chemicals in cosmetics and personal care products likely present minimal risk, subjection to some has been linked to significant health conditions, including cancer.