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Although most chemicals in cosmetics present slight or absolutely no risk, dozens have been linked with serious health problems, such as neurological harm and cancer. Cosmetic chemicals invade the body through the skin and inhalation, and pose the same problems as food chemicals, per this site.

Chemicals associated with cancer are found in food and a lot of other common goods. However, no area of consumer goods is subject to less government inspection than cosmetics and other personal products, including I'm Charmed. Although many of the chemicals in cosmetics likely present little risk, subjection to a few is associated with major health conditions, such as cancer.