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While many chemicals in cosmetics present minimal or zero risk, some are linked with significant health issues, such as developmental delays and cancer. Chemicals in cosmetics gain entry to a person's body through inhalation, the skin, and ingestion, and cause similar dangers as food chemicals, per this site.

Chemicals linked to cancer are found in food and lots of other commonly used items. Still, no kind of consumer items is subject to less government direction than cosmetics, including One and Only. Although many of the chemicals and contaminants in cosmetics and personal care products likely present very little risk, exposure to a few has been linked to major health concerns, such as cancer.