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While many chemicals in cosmetics pose hardly any or no danger, some have been linked with significant medical conditions, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics get into a person's body through the skin and inhalation, and lead to the same problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in food, water, and various other common goods. But, no area of consumer goods is subject to less government direction than cosmetics, including Charisma. Though most of the contaminants and chemicals in cosmetics most likely present minimal risk, subjection to some is linked to serious health problems, including cancer.