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While most chemicals in cosmetic products pose slight or zero threat, dozens have been associated to severe medical issues, including developmental delays and cancer. Cosmetic chemicals gain entry to a person's body through inhalation, ingestion, and the skin, and lead to similar risks as food chemicals, per this site.

Chemicals associated with cancer can be found in food, water, and a lot of other common items. However, no category of consumer items is subject to less government management than cosmetics, including Do I look Buff?. Although many of the contaminants and chemicals in cosmetics most likely pose very little risk, exposure to a few has been associated with worrying health concerns, such as cancer.