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While most chemicals in cosmetics present slight or no threat, several have been associated to severe health issues, including neurological harm and cancer. Chemicals in cosmetics invade a person's body through the skin, inhalation, ingestion and internal use, and lead to similar dangers as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in water, food, and various other everyday goods. However, no kind of consumer goods is accountable to less government oversight than cosmetics, including Loyal. Although most of the chemicals and contaminants in cosmetics likely present little risk, exposure to a few has been associated with major health problems, including cancer.