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While many chemicals in cosmetic products present slight or zero risk, dozens are associated with severe health problems, including cancer, reproductive and neurological harm, and developmental delays. Chemicals in cosmetics can enter a person's body through inhalation, the skin, and ingestion, and pose similar dangers as food chemicals, per this site.

Chemicals associated with cancer can be found in water, food, and various other common products. However, no type of consumer products is subject to less government management than cosmetics, including Charming. Though most of the chemicals in cosmetics almost certainly present minimal risk, exposure to some is associated with worrying health issues, including cancer.