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Although the majority of chemicals in cosmetics present limited or no danger, several dozen are associated with significant medical problems, including developmental delays and cancer. Cosmetic chemicals invade the body through the skin, inhalation, ingestion and internal use, and pose the same problems as food chemicals, per this site.

Chemicals linked to cancer are found in food and lots of other everyday goods. But, no group of consumer goods is accountable to less government direction than cosmetics, including Defiant. Although many of the contaminants and chemicals in cosmetics and personal care products likely pose little risk, subjection to a few has been linked to worrying health problems, such as cancer.