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While many chemicals in cosmetics present little or zero threat, some have been linked to significant health conditions, such as cancer, and neurological harm. Chemicals in cosmetics can enter a person's body through the skin, inhalation, ingestion and internal use, and lead to the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food and various other common products. But, no sector of consumer products is subject to less government direction than cosmetics and other personal care products, including Uptown. While many of the contaminants and chemicals in cosmetics and personal care products very likely present minimal risk, subjection to some is associated with major health concerns, such as cancer.