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Though most chemicals in cosmetic products pose very little or absolutely no threat, several are linked with substantial health conditions, such as cancer, and neurological harm. Cosmetic chemicals gain entry to a person's body through ingestion, inhalation, and internal use, and pose the same risks as food chemicals, per this site.

Chemicals and contaminants associated with cancer are found in food and various other everyday items. Still, no sector of consumer items is subject to less government inspection than cosmetics, including Little Miss Sparkle. Though most of the contaminants and chemicals in cosmetics and personal care products almost certainly pose minimal risk, subjection to some is associated with substantial health problems, such as cancer.