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While the majority of chemicals in cosmetics present little or zero threat, some are associated to severe health issues, including cancer, and neurological harm. Chemicals in cosmetics invade a person's body through inhalation, the skin, and ingestion, and lead to similar problems as food chemicals, per this site.

Contaminants and chemicals linked to cancer can be found in food and lots of other everyday goods. But, no group of consumer goods is subject to less government direction than cosmetics and other personal products, including Hot Rod Red. While most of the chemicals and contaminants in cosmetics and personal care products likely pose little risk, being exposed to some has been linked to critical health conditions, including cancer.