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Though many chemicals in cosmetics present very little or zero threat, several are associated with serious medical problems, such as developmental delays and cancer. Cosmetic chemicals enter a person's body through inhalation, ingestion, and the skin, and lead to the same risks as food chemicals, per this site.

Chemicals associated with cancer are found in water, food, and lots of other commonly used items. Still, no area of consumer items is susceptible to less government inspection than cosmetics, including Wicked. While many of the chemicals and contaminants in cosmetics very likely present little risk, subjection to some is associated with major health concerns, including cancer.