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While the majority of chemicals in cosmetics present slight or zero threat, some are associated with severe medical issues, such as cancer, and neurological harm. Cosmetic chemicals can enter a person's body through the skin and inhalation, and cause similar problems as food chemicals, per this site.

Chemicals linked to cancer are found in food, water, and various other commonly used goods. But, no classification of consumer goods is susceptible to less government direction than cosmetics and other personal care products, including PDX Pedix Feet French Gel. Although many of the contaminants and chemicals in cosmetics and personal care products almost certainly present little risk, being exposed to a few has been linked to substantial health problems, such as cancer.