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Although most chemicals in cosmetics pose little or zero threat, dozens are associated to considerable medical conditions, including neurological harm and cancer. Chemicals in cosmetics gain entry to a person's body through the skin, inhalation, ingestion and internal use, and lead to similar risks as food chemicals, per this site.

Chemicals associated with cancer can be found in food and various other commonly used goods. Yet, no sector of consumer goods is subject to less government oversight than cosmetics, including Nail Lacquer - Sun's Up, Top Down. Although many of the contaminants and chemicals in cosmetics likely pose little risk, subjection to some is associated with significant health concerns, such as cancer.