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Though most chemicals in cosmetics pose limited or zero danger, some are associated with serious health problems, such as cancer, and neurological harm. Chemicals in cosmetics can enter a person's body through the skin, inhalation, ingestion and internal use, and cause the same problems as food chemicals, per this site.

Chemicals and contaminants associated with cancer can be found in water, food, and many other common goods. Still, no group of consumer goods is susceptible to less government oversight than cosmetics and other personal care products, including Gel-n-Base in One Gel Polish - Frostbite. Although most of the chemicals in cosmetics and personal care products likely present minimal risk, being exposed to a few has been associated with worrying health issues, such as cancer.