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Though many chemicals in cosmetics present minimal or no threat, some are associated with significant medical conditions, including developmental delays and cancer. Chemicals in cosmetics gain entry to the body through inhalation, ingestion, and the skin, and lead to similar dangers as food chemicals, per this site.

Contaminants and chemicals associated with cancer can be found in food and several other everyday items. Yet, no group of consumer items is subject to less government inspection than cosmetics and other personal care products, including Gel-n-Base in One Gel Polish - Splish Splash. Though most of the chemicals and contaminants in cosmetics and personal care products probably present very little risk, subjection to a few is associated with serious health issues, including cancer.